Activation of lymphocytes

Activation of lymphocytes.

The technique involved in studying the activation of lymphocytes in the resting form, and their recognition as dividing and functional cells was studied, using phase contrast and agar as well as fluid culture. Standardization of technical methods was found to be essential, and the effect of variables was studied. Lymphocytes from human umbilical cord vein blood were found to be spontaneously ac...

Activation of Human Lymphocytes

Lectins and other polyclonal lymphocyte stimulants have been used extensively both to analyze early events in cellular activation and clinically as aids to the assessment of immunocompetence (1-5). Earlier studies of the response of human blood lymphocytes to lectins provided suggestive evidence for heterogeneity of responding lymphocyte populations (6, 7). Chessin et al. (6) showed that the ly...

Activation/Division of Lymphocytes Results

Activation of T lymphocytes in atherosclerotic plaques.

OBJECTIVE To decipher the immunologic mechanisms of plaque maturation and rupture, it is necessary to analyze the phenotypes and distribution of individual lymphocytes that migrate to the plaques, as well as their activation at different stages of plaque formation. METHODS AND RESULTS We developed a protocol to isolate plaque-residing immune cells and analyze their status using polychromatic ...

Hysteresis During Ras Activation in Lymphocytes